What is Ma Huang from Traditional Chinese Medicine?

What is Ma Huang from Traditional Chinese Medicine?

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what is ma huang

A lot of people look for a miracle drug to promote weight loss and improve energy. In the 1990s, the ephedra plant became popular as a likely candidate, and not till after the mid-2000s, it was a normal ingredient used in dietary supplements. Although some research has shown that it could improve metabolism and loss of weight, some safety issues were also noted.

 

The three species of these stubborn plants that are the source of the drug are native to China, where the aerial parts are collected in the fall and dried for medicinal purposes. The scientific name of the plant is Ephedra sinica, E. Equisetina, E. intermedia.The roots of E. Sinica or E. intermedia, known as ma huang gen, are considered drugs in their own right and are used for their sleep-inducing properties. Ma Huang is also referred to as yellow horse, ephedra, and yellow astringent.

 

What is Ma Huang?

Ephedra also called Ma Huang is a condiment used in the preparation of various Traditional Chinese Medicines (TCM) for several centuries. It is mainly used to treat bronchitis, hay fever, and asthma. The plant is also recommended for symptoms of flu and cold, as well as cough, chills, nasal congestion, and fever.

 

Although Ephedra is a freely growing herb, the primary active ingredient of the plant, ephedrine, can be synthesized as medicine. Man-made ephedrine compounds, for example, pseudoephedrine, are usually used in over-the-counter cold treatments and are regulated as medicines. This is different from the regularization of ephedrine alkaloids obtained from the herb itself. These are governed as dietary supplements.

 

Before May 2004, ephedra was marketed as an energy-boosting supplement, a weight-loss product, and an athletic performance booster. Although there is some scientific evidence suggesting that it can improve one’s weight, the overall data on the effectiveness of this herbal supplement has been regarded as controversial and inconclusive. Furthermore, products that contain ephedra and are sold for the causes have been related to a lot of cases of heart arrhythmia ( heart attack/ irregular heartbeats), cases of stroke, and cases of death even. Many of the ephedra-containing products contain caffeine as well, and the mixture of both caffeine and ephedra improves the risk of getting negative side effects.

 

It is crucial to take note that due to the presence of ephedrine in some products, such as dietary supplements, amateur sporting events are not allowed to use them.

 

The Food and Drug Administration (FDA) has banned the use of dietary supplements that contain ephedrine, ma huang, Pinella, Ephedra, or Sida cordifolia. This ban does not include teas ( which are distributed as a normal food) or Chinese traditional herbal remedies that have been recommended by a traditional Chinese doctor.

 

Improving Metabolic Rates and Fat Burn

Quite a number of the research into the effects of ephedra on weight loss was done in the 1980s and early 2000s, before the ban on ephedrine supplements. Some components of ephedrine can affect your body, but the most notable of the effects are probably due to ephedrine.

 

Various studies have shown that ephedrine increases the resting number of metabolism i.e (the number of calories the body utilizes in a resting state). This may be a result of an increase in the number of calories burned by the muscles. Ephedrine can as enhance the process of burning fat in the body as well.

 

It was found in research that the number of calories burned off in the space of 24 hours was higher by 3.6% when ephedrine was used by adults of sound health, in comparison to when they used a placebo.

 

Another researcher discovered that once people went on an extremely low-calorie diet, their rate of metabolism dropped. However, this became partly avoided by using ephedrine. Added to the short-time period adjustments in metabolism, a few researchers concluded that ephedrine can encourage weight and fat loss over a longer period. In five studies of ephedrine while being compared to a placebo, ephedrine brought about a weight reduction of three pounds (1.3kg) per month greater than a placebo, for as much as four months. However, there is a lack of long-term data that can support the benefits of ephedrine for the loss of weight.

 

Furthermore, a lot of studies on ephedrine test the weight-loss of caffeine and ephedrine, in place of ephedrine alone.

 

Does it work well or not so well with caffine?

 

Various studies testing the weight-loss impact of ephedrine have mixed the ingredient with caffeine. The mix of the two seems to have greater impacts on your body than taking either of them alone. For instance, caffeine with ephedrine boosts the rate of metabolism more than only ephedrine.

 

In a study of obese and healthy overweight adults, the mixture of 24mgb of Ephedra and 79mg of caffeine increased the metabolic rate by 8% in 2 hours, in comparison to placebo. Some studies have even indicated that ephedrine and caffeine alone have no impact on weight loss, but the mixture of both produces a loss of weight. Taking the combination of ephedra and caffeine three times daily for 12 weeks reduced body fat by 7.9% compared to just 1.9% with placebo.

 

In another 6-month study of 167 obese and overweight individuals, dietary supplements containing ephedrine and caffeine were compared to placebo in a weight loss program. The group receiving ephedrine lost 9.5 pounds (4.3 kg) of fat in comparison to the group taking placebo, which lost only 5.9 pounds (2.7 kg) of fat.

 

The group taking ephedrine also reduced LDL (bad) cholesterol and body weight more than the group taking placebo. Overall, the available evidence suggests that products containing ephedrine, especially when combined with caffeine, may increase weight and fat loss.

 

Conclusion

Ma Huang is a stimulant herb obtained from the roots of Ephedra sinica. Many people have found it beneficial for weight loss, and also treating nasal congestion, common cold, asthma, and some other conditions. However, these uses have no scientific backing. However, the herb is banned in the US as there have been reports of life-threatening conditions and even death.

 

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What is CBG (cannabigerol) & what does this cannabinoid do?

What is CBG (cannabigerol) & what does this cannabinoid do?

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If you’ve spent any time online (like here) or at your local dispensary, the most popular cannabinoids, THC (tetrahydrocannabinol) and CBD (cannabidiol), and their effects might seem like old news. But as both the science and legislation around weed research improve, so does our access to the rest of the 100+ cannabinoids found in the plant, each with their own unique set of properties and experiences. 

CBG, or cannabigerol, called a minor cannabinoid since it manifests in trace amounts in most strains, has been around for years, and makes a worthy addition to your weed encyclopedia and next smoke sesh. 

The origins of CBG

While you may not have heard about CBG, humans have reaped its benefits for millennia, in both cannabis and hemp plants. It was first synthesized in 1964, alongside THC, and has been studied extensively for its medicinal potential. It’s often called the “mother of all cannabinoids” because without it, cannabis would have no high. 

You know the saying all roads lead to Rome? Well all cannabinoids lead back to CBG. 

Figure 1: CBG-A is the chemical precursor of THCA, CBDA, and CBCA (not shown). Enzymes within cannabis turn CBGA into either THCA or CBDA, which can be subsequently decarboxylated (“activated”) by light or heat energy to create THC or CBD. (Amy Phung/Leafly)

As young cannabis plants mature and begin budding, various enzymes and compounds combine to create the precursor to CBG—also called an “early-phase” cannabinoid—called CBGA. CBGA is where all cannabinoids start; as the plant nears the end of its grow cycle and absorbs more and more UV light, CBGA breaks down and converts into THCA and CBDA, the acidic precursors to our two favorite and most prominent cannabinoids, THC and CBD. Unless bred to do so, in most cases, only a very small amount will become CBG. 

CBG in hemp plants

Thanks to the 2018 Farm Bill, hemp plants that contain less than 0.3% THC are federally legal. CBGA is present in both cannabis and hemp plants, and since it directly correlates to hemp plants’ CBG and CBD potency, farmers can derive CBG from hemp plants. In fact, numerous hemp farmers now breed and grow CBG-rich strains that don’t require a trip to the dispensary or a medical marijuana card to access.

Because CBG isn’t abundant in most strains, breeders have begun crossbreeding plants to achieve higher levels of the cannabinoid. Farms like Oregon CBD have won multiple awards for their White CBG strain, which contains around 10% CBG and less than 0.3% THC. 

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Medical benefits of CBG

Despite its paltry numbers in mature weed buds, when isolated, CBG demonstrates a number of benefits to the human body. 

CBG, like CBD, is non-intoxicating and does not impart a high, despite its connection to THC. Research indicates it can bind to both CB1 and CB2 receptors within the body’s endocannabinoid system, meaning it not only interacts directly with the body’s internal systems, but can also counteract the effects of other cannabinoids, such as THC. 

The human body’s endocannabinoid system (ECS) keeps the body in a balanced state of homeostasis via innumerable receptors throughout limbs, organs, nerves, and systems (e.g., digestive, immune, reproductive, and more). 

A 2021 patient survey indicated a majority of patients found CBG-dominant products effective in treating their chronic pain, anxiety, and insomnia, among other conditions. 

While there are still gaps to fill in the research of CBG, early findings indicate it has numerous health benefits: 

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Since CBG is non-intoxicating and can be derived from hemp plants, which are federally legal, it’s not a scheduled substance. This means scientists can now access funding to continue studying the full potential of this special cannabinoid. The best is yet to come!    

Differences of effects in CBG and CBD

The recent influx of cannabinoids on the market means there’s a lot more info to keep track of. At a glance, CBG may seem like a variation of CBD, as they are both non-intoxicating and exhibit similar anti-inflammatory properties. But there are key differences that may change how you consume each. 

CBG and CBD don’t bind to the same receptors in the body, and also differ on a molecular level. Because CBG can bind to the same receptors as THC, it can potentially address issues that pertain to the nervous system, including conditions mentioned above, such as glaucoma, migraines, muscle soreness and inducing appetite. 

CBD, on the other hand, may be more effective for immunity-related conditions and regulating mood disorders.  

In research, both have promise for counteracting the effects of THC, and neither intoxicate the consumer even when taken at high doses.

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Weed strains with CBG

Since CBG primarily becomes other cannabinoids, most flower available to buy in licensed adult-use dispensaries will contain less than 1% CBG. 

There are specific strains, such as White CBG, that are bred by hemp farms to yield a higher CBG level, and won’t impart a high. However, even though hemp farmers can legally grow smokable CBG hemp and manufacture CBG products in states that allow it, they aren’t beholden to the same testing standards as cannabis.

Inhaling and ingesting cannabis products with a broad spectrum of cannabinoids and terpenes may have better medicinal and recreational efficacy than in isolation for some individuals—this is called the entourage effect, or whole-plant medicine. Even if what you’re consuming isn’t CBG-dominant, CBG can still contribute to an enjoyable or therapeutic experience.  

We’ve rounded up some of the best high-THC strains that also express CBG: 

CBG products are popping up more and more in the adult-use, medical marijuana, and hemp markets as this cannabinoid proves again and again it’s worth a try.  

Amelia Williams's Bio Image

Amelia Williams

New York-based freelance cannabis journalist Amelia Williams is a graduate of San Francisco State University’s journalism program, and a former budtender. Williams has contributed to the San Francisco Chronicle’s GreenState, MG Magazine, Culture Magazine, and Cannabis Now, Kirkus Reviews, and The Bold Italic.

View Amelia Williams’s articles

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New York Senate Passes Gray Market Cannabis Bill

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The New York Senate voted this week to approve a bill to crack down on the state’s cannabis gray market, giving regulators the authority to seize illicit weed and increasing fines for unlicensed operators. State Senator Liz Krueger introduced the measure on Sunday and by Wednesday, the Senate had voted to approve the bill, offering an indication of the legislature’s interest in addressing New York’s unregulated pot market before legal sales of recreational cannabis begin later this year.

Justin Flagg, a spokesperson for Krueger, said that the bill is designed to empower the New York Office of Cannabis Management (OCM) and the Department of Taxation and Finance to address unregulated cannabis retailers, which have become brazenly ubiquitous in Manhattan and other areas since state lawmakers legalized adult-use cannabis last year. The OCM is currently working to establish rules for the regulated market, which should begin licensed recreational cannabis sales by the end of 2022.

“This bill is aimed at gray market operators such as retail cannabis stores that have emerged during the period after legalization but before licensed businesses begin operating,” Flagg said in an email quoted by Syracuse.com. 

Flagg added that Krueger drafted the legislation with cooperation from OCM and the tax and finance department, noting that their action was “prompted by the difficulty of enforcement against several illegal cannabis stores that have been hard to shut down under the existing statute.”

The bill gives the OCM the authority to seize illicit cannabis and expands the authority of the Taxation and Finance Department to assess fines against unlicensed cannabis operators. The measure also doubles civil penalties for anyone who knowingly possesses illicit pot, which is defined as taxable cannabis products for which no tax has been paid. Flagg clarified that the legislation applies to any cannabis product that was not grown by or purchased from a cannabis business licensed by the state.

Fines for Illicit Weed Doubled in New York

Fines for illicit cannabis would be increased from $200 per ounce of flower to $400 per ounce. Fines for other cannabis products would also be doubled, with edibles rising to $10 per milligram of THC and concentrates to $100 per gram, while the fine for each illicit cannabis plant would jump to $1,000. The bill also allows the Taxation and Finance Department to revoke certificates of registration for businesses that sell or possess illicit cannabis.

Flagg said that restraining the illicit market is in part a safety issue because unlicensed operators do not follow packaging rules and other regulations designed to curtail cannabis use by children.

“Addressing these illegal operators will help ensure that licensed equity operators have the opportunity to succeed and also help ensure that cannabis products are sold in a responsible way,” Flagg said.

Joshua Waterman, a cannabis grower and the co-founder of the Legacy Growers Association, told local media that Krueger’s bill was drafted with good intentions, but he does not support the legislation.

“Although the idea of shutting down dispensaries that are flooding the market with … products from other states is something we would support, we just don’t see that in this bill,” he said. “I’m afraid this will end up being another way for the state to fine and penalize lower-class individuals, especially minorities.”

Waterman added that the bill will strengthen legacy growers’ mistrust of legalization and make them less likely to join the ranks of the regulated market, which has been a goal advanced by lawmakers and regulators.

“The state and the OCM keep saying they want to include and incentivize legacy people to enter the legal market,” Waterman said. “Putting out a bill to stop legacy operations before releasing applications for licensing is disgraceful, and truly shows where lawmakers stand when it comes to the legends that created the cannabis industry without ever asking for their support.”

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The Kids Can’t Buy Weed

The Kids Can’t Buy Weed

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cannabis dispensaries don't sell to minors

Have you heard this one before, “it will be so much easier for the youth to get their hands on cannabis!” This is the argument that prohibitionists have touted for decades and according to them, the moment you legalize cannabis it will be available everywhere.

 

Kids will be able to walk into a dispensary and some overgrown hippie would easily sell them weed….right? Well, it turns out that a recent study in California found that 100% of Cannabis dispensaries that were tested were compliant in checking ID prior to sale.

 

This was reported on Marijuana Moment where they covered the study.

 

“It was somewhat surprising that there was 100 percent compliance with the ID policy to keep underage patrons from purchasing marijuana directly from licensed outlets,” the authors of the study, published this month in the Journal of Safety Research, wrote. “However, that was consistent with what was observed in two other states, Washington and Colorado.”

 

In other words, the cannabis industry has no real interest in selling cannabis illegally to the youth. Compliance is their friend and what this does in turn is actually make “getting cannabis” more difficult for the kids.

 

This doesn’t mean that kids can’t get their hands on cannabis, it only means that the legal industry is not contributing to their consumption.

 

“It appears that licensed recreational marijuana outlets in California are checking young patrons for identification of their age. Therefore, it is unlikely that youth are purchasing marijuana directly from these outlets,” the new study says. “It is more likely they are using other sources, such as asking an adult to purchase it for them, obtaining it from older friends or siblings, and using it at parties where the marijuana use might be shared.” – Marijuana Moment

 

This is virtually the same for alcohol, and is something that you cannot stop because there will always be older adults buying stuff for younger people. An older brother, uncle, or even a home grow from a teen that doesn’t get too much parental supervision can all be sources where the youth source their weed.

 

The Youth in General Consume Less

 

The strange thing that happened since legalization is that youth consumption rates stayed pretty much the same or reduced post legalization as reported in the Guardian.

 

Researchers from the Washington University School of Medicine in St Louis surveyed 216,852 teenagers from all 50 states and found that the number of adolescents with marijuana-related disorders dropped by 24% from 2002 to 2013. During that period, overall teen pot use also decreased by 10%, despite the fact that more than a dozen states legalized medical marijuana and decriminalized the drug during that time. – The Guardian, 2016

 

While it’s true that this article is five years old, the fact of the matter is that the findings remain consistent. While the Youth prefer cannabis and mushrooms over alcohol, fewer of them are using cannabis. In other words, it seems that cannabis legalization removed the “edge” from the use of cannabis.

 

When I was a teenager, cannabis was seen as a “rebellious act” by some…not by me, I just loved smoking pot! However, others would rebel by smoking weed.

 

These days, rebellion takes on different forms. I’m not going speculate what is the “flavor of the day” for youth rebellion…but what conclusions we can draw from all this noise is that “legalizing cannabis” doesn’t make it easier for kids to get their hands on weed.

 

In fact, no legal establishment will sell cannabis due to the fines and punishments associated with selling to a minor.

 

This will also not change in the coming years.

 

Legal makes it harder…and safer!  

 

Legal businesses will never sell to a minor. The weed sold in these places need to go through strict standards and regulatory checks, meaning that it’s also safer to consume than untested street weed (technically).

 

If this works with weed…why wouldn’t it work with other drugs too? Why is it that we live in a society that frowns upon the individual’s right to get blitzed? Why can’t I buy pharmaceutical grade LSD from a store if I’m over the age of 21?

 

Why am I allowed to smoke weed, drink alcohol and pop pills legally – but can’t eat some mushrooms?

 

If every dispensary could sell “drugs” in general, compliance would still remain 100% and if you’re worried about these 3rd-party Free agents giving kids drugs…increase the penalties for them. But we should never punish the whole of society for the potential bad actions of a few people.

 

I believe that if we legalize and regulate all drugs like Marijuana, we would not only have a safer society…but we would begin to see a dawn of a new age of enlightenment as millions of adults would have the legal right to experience a psychedelic experience – to heal, to shift their perspectives and to explore their own consciousness.

 

Legalization works! Let’s do it for all drugs!

 

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Summer Fridays are back with Heavy Hitters ‘Sip & Smoke’

Summer Fridays are back with Heavy Hitters ‘Sip & Smoke’

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